Plant Brainrot Simulator Mutations Guide

Mutations are one of the most exciting progression mechanics in Plant Brainrot Simulator. A mutation changes how a plant attacks (and sometimes how it controls enemies), so the right mutation can make your team feel completely different even if you’re using the same base plants.

This page focuses on one thing: Plant Brainrot Simulator mutations — the mutation types, what they do, which fruits grant them, and the most common questions players search for (like Shadow mutation and Reversion Fruit).

Plant Brainrot Simulator mutation types (quick list)

The game currently features several core mutation types. Here’s the in-game type list screenshot for a quick overview:

Below, we break down each type in plain English so you can decide which mutation fits your build and stage of the game.

What are mutations in Plant Brainrot Simulator?

A mutation is a modifier applied to a plant that changes its attack behavior. In practice, mutations usually fall into one of these roles:

• Control (freeze, slow, knockback) to keep enemies from reaching you
• Damage over time (burn) to add consistent extra damage
• Burst / crowd damage (AOE) to clear groups faster
• Utility (reversion / reroll behavior) to undo an unwanted mutation

Unlike simple stat upgrades, mutations add new combat effects. That’s why many players treat mutations as a “power spike” goal — once you get a mutation that matches your team, your run can feel smoother immediately.

Mutation fruits: which fruit gives which mutation?

In Plant Brainrot Simulator, mutations are strongly tied to fruits. Each mutation fruit generally corresponds to a specific mutation type:

Tip: Fruits can also appear as rewards from events/updates or redeemable codes. If you want freebies, check the latest codes here: /codes.

Frozen mutation: what it does and when it’s good

Frozen is a control-focused mutation. When it triggers, your plant can freeze enemies for a short time, which can:

• Buy time in tight waves
• Improve survivability if your team is still weak
• Make boss fights feel safer by reducing incoming pressure

Frozen is especially useful early and mid game because control effects can matter more than raw DPS when your damage isn’t high yet.

Flame (Fire) mutation: extra damage over time

Flame (sometimes referred to as Fire) adds a burn-like effect that can deal extra damage. Even if your base plant isn’t top-tier, Flame can help you:

• Finish off enemies that barely survive your hits
• Add consistent chip damage while you focus on upgrades

Flame tends to feel best when your plants attack frequently, because you get more chances to apply or refresh the burn effect.

Venom (Poison) mutation: slow and debuff

Players often call this mutation Venom, while the in-game list may label it as Poison. In practical terms, it’s a slow effect — your plant’s attacks can slow enemies down.

Is Venom the same as Poison?

In most community discussions, “Venom” and “Poison” refer to the same mutation type. The key takeaway is the effect: slowing enemies (not necessarily a damage-over-time poison). If your game UI describes extra damage, trust the in-game wording for your current version.

Venom/Poison is a great “all-rounder” mutation because slowing enemies helps almost any team composition.

Shadow mutation (Darkness): knockback and high impact

Many players refer to the Dark / Darkness mutation as the Shadow mutation. The core effect shown in-game is knockback — your plant’s attacks can knock enemies back, which can dramatically reduce how often enemies reach your frontline.

What does Shadow mutation do?

In short: Shadow (Darkness) = knockback control, and it often feels like a late-game power spike because knockback can create breathing room even in hard waves.

Is Shadow mutation the highest multiplier?

Community consensus often treats Shadow/Darkness as one of the strongest overall mutations, especially when you value both control and damage feel. Exact multipliers can change between updates, so treat “best mutation” as situational:

• If you need survival/control, Shadow knockback is extremely valuable
• If you need wave clear, Bomb AOE can outperform in crowded stages
• If you need consistent slow, Venom/Poison can keep enemies managed

Bomb mutation: AOE wave clear

Bomb is the mutation to think about when your biggest problem is too many enemies at once. Bomb attacks can deal area-of-effect (AOE) damage, helping you:

• Clear packs faster
• Stabilize runs when waves overwhelm single-target DPS

Bomb may show slightly lower single-target performance compared to high-impact options, but it shines when stages get crowded.

When should you mutate your plants? (best timing)

If you’re early in progression, it’s tempting to mutate everything immediately. However, many experienced players recommend a safer approach:

• Don’t mutate too early if you still replace plants frequently
• Consider mutating only when a plant is already a long-term keeper (for many players, that means around 5 stars)

The reason is simple: mutations can be hard to replace if you get one you don’t like, and some updates may introduce chance-based mutation behavior during merges/upgrades. If you prefer consistency, mutating later reduces regret.

Reversion Fruit: how it works (and why it matters)

Reversion Fruit is the “undo button” for mutations. It can only be used on a mutated plant, and it reverts the plant back to its original (non-mutated) state.

Reversion is useful when:

• You accidentally applied the wrong mutation fruit
• You got a mutation you don’t want for your build
• You want to switch to a different mutation type later

Think of Reversion Fruit as a late-game quality-of-life item: it helps you experiment without permanently locking in a bad outcome.

FAQ: Plant Brainrot Simulator mutations

Can plants mutate when merging/fusing?

Depending on the current update, the game may add chances for mutations to appear during certain actions (like merging/upgrading). If you dislike randomness, mutate later and keep Reversion Fruit available as a backup.

What should I do if I mutated too early?

If you’re not happy with the result, use Reversion Fruit to remove the mutation. Then wait until you have a stable, long-term plant before mutating again.

Does mutation fail give weight (+0.5kg)?

Some players report that failed mutation attempts can grant a small weight gain (commonly described as +0.5kg per fail) and that repeating “mutate → revert” can increase plant weight over time.

This behavior can be patch-dependent. If your current version shows a “mutation fail” weight reward in-game, you can test it safely with a low-value plant before investing rare fruits.

Is there a quick “weight loop” with Reversion Fruit?

A simple community loop is:

1. Apply a mutation fruit to a target plant
2. Use Reversion Fruit to revert it
3. Repeat (only if your version rewards weight on fails/reversions)

Use this carefully — treat it as a pro tip, not a guaranteed mechanic across all updates. A dedicated pro tips guide will cover weight strategies in more detail.